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MACC
Awards

OUR ACHIEVEMENTS

Current and past funding

2010

Apr 10 – Mar 14

NMRC/CG/NUHS/2010, NUHS Centre Grant – Memory Ageing and Cognition Centre; PI: A/Prof Christopher Chen SGD6,000,000
2011

Mar 11 – Mar 16

GSK ACE award – Retinal Vascular Signs as Novel Biomarkers of Dementia; Co-PI: A/Prof Christopher Chen SGD1,011,825

Jul 11 – Feb 14

NMRC/1288/2011 – Chinese Medicine Neuroaid Efficacy on Stroke Recovery (CHIMES) Study; PI: A/Prof Christopher Chen SGD743,677
2012

Jan 12 – Jan 17

NMRC/CSA/032/2011, Clinician Scientist Award (SI category) – Translational Research in Dementia: Mechanisms of Diseases, Pathophysiology and Biomarker Discovery; PI: A/Prof Christopher Chen SGD1,750,000
2013

Apr 13 – Mar 18

NMRC/CG/013/2013, NMRC Centre Grant - NUHS - Metabolic Medicine, Infectious Diseases, Neuroscience Enablers (MINE) – Cognitive Assessment Core; PI: A/Prof Christopher Chen SGD3,100,000

Jun 13 – Jun 16

HSRG/041/2013 – The Feasibility and Validation of an Informant-Based Cognitive Screening Instrument in the Primary Healthcare Setting; PI: A/Prof Christopher Chen SGD200,000
2015

May 15 – Mar 18

NUHS CIRC Core Seed Funding - Correlating brain glutamate levels with cognitive function and amyloid burden in ApoE4 Alzheimer’s disease; PI: A/Prof Christopher Chen SGD50,000

May 15 – Apr 18

NUHSRO/2014/102/AF-WORLDCLASS/01 - Preclinical and clinical investigations of neurodegeneration and age-associated cognitive impairments; Co-PI: A/Prof Christopher Chen (PI: Prof Carlos Ibanez) SGD2,000,000 (total approved grant budget)
2016

Mar 16 – Mar 18

NMRC/MOHIAFCat1/0060/2016 - The Alzheimer’s disease THErapy with NEuroaid (ATHENE) Study : Assessing the Safety and Efficacy of Neuroaid II (MLC901) in patients with mild to moderate Alzheimer's disease stable on Cholinesterase inhibitors or Memantine: A Randomized, double blind, placebo controlled trial; PI: A/Prof Christopher Chen SGD675,000

Mar 16 – Mar 18

NUHS CIRC Core Seed Funding - An investigation of visual speed of processing in MCI patients; PI: A/Prof Christopher Chen SGD49,700

May 16 – Apr 18

DUKE / DUKE-NUS Research Collaboration Pilot Project – Ocular Markers of Alzheimer’s Disease: OMEGA Study; Co-I: A/Prof Christopher Chen (PI: Prof Wong Tien Yin) SGD100,000

Aug 16 – Aug 19

NMRC/CIRG/1446/2016 - Etiology of Cortical Cerebral Microinfarcts and Impact on Brain Function and Long Term Outcomes; PI: A/Prof Christopher Chen SGD1,472,463.02
2017

Jan 17 – Jan 22

NMRC/CSA-SI/0007/2016 - Translational Research in Vascular Biomarkers of Dementia: Discovery, Validation and Assessment of Clinical Utility; PI: A/Prof Christopher Chen SGD1,750,000

Feb 17 – Feb 19

Health and Medical Research Fund (application no. 04153506) – Novel retinal imaging biomarkers for cognitive decline; Collaborator: A/Prof Christopher Chen (PI: Asst/Prof Carol Cheung Yim-Lui) HKD1,190,482

Mar 17 – Mar 19

NUHS O-CRG 2016 Oct -24 - Telomere length as a peripheral biomarker of cerebrovascular disease and neurodegeneration in dementia; Co-I: A/Prof Christopher Chen (PI: Asst/Prof Mitchell Lai) SGD179,999

Jun 17 - Jun 20

AMED2016-SG013 - Targeting Age-Associated White Matter Lesions; Co-I: A/Prof Christopher Chen (PI: Prof Peter Wong) SGD250,000

Jun 17 - May 19

NUHSRO/2017/014/Cambridge/01 - Cognitive and neuropsychiatric profiles of amyloid burden and cerebrovascular disease in elderly with mild cognitive impairment; NUHS PI: A/Prof Christopher Chen, Cambridge PI: Prof John O'Brien SGD30,000

June 17 – May 21

NUHS MCG CORE 4 NCC OOE / EOM - Centre Grant - Diabetes, Tuberculosis and Neuroscience Core 4 – Neuro Cognitive Core, PI: A/Prof Christopher Chen (SGD$552,271 disbursed in 2018)
2018

Feb 18 – Feb 20

Machine learning tools for personalised diagnosis in dementia, PI: A/Prof Christopher Chen SGD$121,720

Apr 18 – Mar 19

NUHSCG/2017/Bridging/01 (NMRC/CG/M009/2017) - MACC Biomarker Discovery Bridging Fund, PI: A/Prof Christopher Chen SGD$100,000

Jul 18 – Mar 20

Functionalageing/SINGER/FY2018 - SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER) Pilot study, PI: A/Prof Christopher Chen SGD$420,000

Jul 18 – Jul 21

NMRC/CIRG/1485/2018 - Mechanisms of decline in vascular cognitive impairment, PI: A/Prof Christopher Chen SGD$1,493,000
2019

Feb 2019- Dec 2021

NUS-USYD Strategic Partnership 2019 - Intensive targeting of blood pressure to reduce dementia and small‐vessel disease in individuals who have survived an intracerebral haemorrhage: a multi‐site double‐blind placebo controlled randomized controlled trial and cognitive validity study, SGD$9925

Oct 2019 – Mar 2021

DDOP Clinical trial - Clinical assessment of the use of reverse transcriptase inhibitors in patients with mild cognitive impairment, SGD$341,000
2021

Jan 2021 – Jan 2026

NMRC Open Fund Large Collaborative Grant Call (OF-LCG) (May 2019) - Prevention of and Biomarkers for Vascular Cognitive Impairment, SGD$10,000,000

Awards

Local

  • National Medical Research Council
    1. Clinician Scientist Award (2017):
      Translational Research in Vascular Biomarkers of Dementia: Discovery, Validation and Assessment of Clinical Utility
      Assoc. Prof. Christopher Chen, NUS Yong Loo Lin School of Medicine (YLLSOM) National University Hospital System (NUHS) (Neurology)
    2. STaR Investigator Award (2013):
      Synaptic Injury in Alzheimer Disease: Mechanisms and Treatment
      Prof Edward Koo, NUS Yong Loo Lin School of Medicine (YLLSOM) National University Hospital System (NUHS) (Neurology)
    3. Clinician Scientist Award – Investigators (2012):
      Retinal Vascular Imaging Study in Transient Ischemic Attacks (REVISTA)
      Dr Mohammad Kamran Ikram, Singapore Eye Research Institute (SERI) Singapore National Eye Centre (SNEC) YLLSOM (Opthalmology)
    4. Clinician Scientist Award - Senior Investigators (2012):
      Translational Research in Dementia: Mechanisms of Disease, Pathophysiology and Biomarker Discovery
      Assoc. Prof. Christopher Chen, NUS Yong Loo Lin School of Medicine (YLLSOM) National University Hospital System (NUHS) (Neurology)
    5. Research Training Fellowship (2011)
      Ms Dong Yanhong Catherine, NUS Department of Pharmacology Yong Loo Lin School of Medicine (YLLSOM)
  • National University Health System (NUHS)
    1. A/Prof Christopher Chen
    2. Dr Saima Hilal
    3. National Clinician Scientist Program (NCSP) Award (2014)
      Dr Dong Yanhong Catherine, NUS Department of Pharmacology Yong Loo Lin School of Medicine (YLLSOM)
  • Others
    1. College of Physicians Lecturer (2019)
      A/Prof Christopher Chen Li Hsian
    2. Galloway Lecturer by the Academy of Medicine (2017)
      A/Prof Christopher Chen Li Hsian
    3. Excellence Award by the Glaxo Smith Kline Academic Centre (2010)
      A/Prof Christopher Chen Li Hsian
    4. A/Prof Christopher Chen Li Hsian and team (Dr S Young, Dr NV Ramani, Ms Connie Teo and Mr David Picard)

International

  • Simeon Marasigan Memorial Lecture, Dementia Society of the Philippines (2020)
    A/Prof Christopher Chen Li Hsian
  • Honorary Fellow of the Japanese Society of Neurology (2019)
    A/Prof Christopher Chen Li Hsian
  • Travel Grant Award at the International Congress of Otolaryngology-Head and Neck Surgery (2019)
    Dr Bibek Gyanwali
  • Early Career Investigator Travel Bursary at the 29th International Symposium on Cerebral Blood Flow Metabolism and Function (Brain and Brain PET) (2019)
    Dr Bibek Gyanwali
  • Best poster presentation at the 13th Asian Society Against Dementia Conference (2019)
    Dr Saima Hilal
  • Travel grant by The International Society of Vascular Behavioral and Cognitive Disorders for presenting paper on, ‘Enlarged perivascular spaces and cognition: meta-analysis of four cohorts in UNIVRSE consortium’ (2018)
    Dr Saima Hilal
  • Travel Fellowship, Alzheimer’s Association International Conference for presenting paper on, ‘Cerebral cortical microinfarcts and cognitive decline in Asian memory clinic population’ (2018)
    Dr Saima Hilal
  • Travel Fellowship by Alzheimer’s Association International Conference for presenting paper on, ‘Subclinical cardiac biomarkers and clinically manifest cardiac diseases are related to cortical cerebral microinfarcts in memory clinic patients’. (2016)
    Dr Saima Hilal
  • Best oral presentation award (Annual Graduate Scientific Conference), National University of Singapore, for presenting paper on, ‘Cerebral cortical microinfarcts on 3 Tesla MRI: a novel marker of cerebrovascular disease’ (2016)
    Dr Saima Hilal
  • International Training Grant (Internationale Stichting Alzheimer Onderzoek), Netherlands for training on ‘Lesion symptom mapping for white matter hyperintensity lesions’ (2015)
    Dr Saima Hilal
  • Young Investigator Award at The International Society of Vascular Behavioral and Cognitive Disorders Conference (2015)
    Dr Saima Hilal
  • Best oral and poster presenters at the 9th Asian Society Against Dementia Conference (2015)
    • Dr. Saima Hilal and Shaik Muhammad Amin for winning best oral awards
    • Dr. Xu Xin and Chan Qun Lin for winning best poster award
  • MV Arunachalam Endowment Orator (2015)
    A/Prof Christopher Chen Li Hsian
  • Best paper award at ASEAN Neuroscience 2015 Conference (2015)
    Dr. Venketasubramanian N
  • Travel Fellowship by Alzheimer’s Association International Conference for presenting paper on, ‘High-definition optical coherence tomography and MRI-defined neuroimaging markers in an Asian population’. (2014)
    Dr Saima Hilal
  • Best poster presentation prize at the 8th Asian Society Against Dementia Conference (2014)
    Dr. Summer Xin Xu
  • Recipient of prestigious Endeavour Research Fellowship and Dean's List Award for her PhD (2014)
    Dr. Catherine Dong
  • Best oral presenter award at the 7th Asian Society Against Dementia Conference (2013)
    Dr. Saima Hilal
  • Best oral and poster award at the 6th Asian Society Against Dementia and 17th Malaysian Conference on Psychological Medicine Awards (2012)
    • Lee Wah Yean (first author) and presented by Dong YanHong for winning best oral award
    • Dong YanHong (first author) and presented by Dong YanHong
  • Young Investigator Award at 13th Asian Oceanian Congress of Neurology Award (2012)
    Koay Way Inn