2010
Apr 10 – Mar 14
NMRC/CG/NUHS/2010, NUHS Centre Grant – Memory Ageing and Cognition Centre; PI: A/Prof Christopher Chen SGD6,000,000
2011
Mar 11 – Mar 16
GSK ACE award – Retinal Vascular Signs as Novel Biomarkers of Dementia; Co-PI: A/Prof Christopher Chen SGD1,011,825
Jul 11 – Feb 14
NMRC/1288/2011 – Chinese Medicine Neuroaid Efficacy on Stroke Recovery (CHIMES) Study; PI: A/Prof Christopher Chen SGD743,677
2012
Jan 12 – Jan 17
NMRC/CSA/032/2011, Clinician Scientist Award (SI category) – Translational Research in Dementia: Mechanisms of Diseases, Pathophysiology and Biomarker Discovery; PI: A/Prof Christopher Chen SGD1,750,000
2013
Apr 13 – Mar 18
NMRC/CG/013/2013, NMRC Centre Grant - NUHS - Metabolic Medicine, Infectious Diseases, Neuroscience Enablers (MINE) – Cognitive Assessment Core; PI: A/Prof Christopher Chen SGD3,100,000
Jun 13 – Jun 16
HSRG/041/2013 – The Feasibility and Validation of an Informant-Based Cognitive Screening Instrument in the Primary Healthcare Setting; PI: A/Prof Christopher Chen SGD200,000
2015
May 15 – Mar 18
NUHS CIRC Core Seed Funding - Correlating brain glutamate levels with cognitive function and amyloid burden in ApoE4 Alzheimer’s disease; PI: A/Prof Christopher Chen SGD50,000
May 15 – Apr 18
NUHSRO/2014/102/AF-WORLDCLASS/01 - Preclinical and clinical investigations of neurodegeneration and age-associated cognitive impairments; Co-PI: A/Prof Christopher Chen (PI: Prof Carlos Ibanez) SGD2,000,000 (total approved grant budget)
2016
Mar 16 – Mar 18
NMRC/MOHIAFCat1/0060/2016 - The Alzheimer’s disease THErapy with NEuroaid (ATHENE) Study : Assessing the Safety and Efficacy of Neuroaid II (MLC901) in patients with mild to moderate Alzheimer's disease stable on Cholinesterase inhibitors or Memantine: A Randomized, double blind, placebo controlled trial; PI: A/Prof Christopher Chen SGD675,000
Mar 16 – Mar 18
NUHS CIRC Core Seed Funding - An investigation of visual speed of processing in MCI patients; PI: A/Prof Christopher Chen SGD49,700
May 16 – Apr 18
DUKE / DUKE-NUS Research Collaboration Pilot Project – Ocular Markers of Alzheimer’s Disease: OMEGA Study; Co-I: A/Prof Christopher Chen (PI: Prof Wong Tien Yin) SGD100,000
Aug 16 – Aug 19
NMRC/CIRG/1446/2016 - Etiology of Cortical Cerebral Microinfarcts and Impact on Brain Function and Long Term Outcomes; PI: A/Prof Christopher Chen SGD1,472,463.02
2017
Jan 17 – Jan 22
NMRC/CSA-SI/0007/2016 - Translational Research in Vascular Biomarkers of Dementia: Discovery, Validation and Assessment of Clinical Utility; PI: A/Prof Christopher Chen SGD1,750,000
Feb 17 – Feb 19
Health and Medical Research Fund (application no. 04153506) – Novel retinal imaging biomarkers for cognitive decline; Collaborator: A/Prof Christopher Chen (PI: Asst/Prof Carol Cheung Yim-Lui) HKD1,190,482
Mar 17 – Mar 19
NUHS O-CRG 2016 Oct -24 - Telomere length as a peripheral biomarker of cerebrovascular disease and neurodegeneration in dementia; Co-I: A/Prof Christopher Chen (PI: Asst/Prof Mitchell Lai) SGD179,999
Jun 17 - Jun 20
AMED2016-SG013 - Targeting Age-Associated White Matter Lesions; Co-I: A/Prof Christopher Chen (PI: Prof Peter Wong) SGD250,000
Jun 17 - May 19
NUHSRO/2017/014/Cambridge/01 - Cognitive and neuropsychiatric profiles of amyloid burden and cerebrovascular disease in elderly with mild cognitive impairment; NUHS PI: A/Prof Christopher Chen, Cambridge PI: Prof John O'Brien SGD30,000
June 17 – May 21
NUHS MCG CORE 4 NCC OOE / EOM - Centre Grant - Diabetes, Tuberculosis and Neuroscience Core 4 – Neuro Cognitive Core, PI: A/Prof Christopher Chen (SGD$552,271 disbursed in 2018)
2018
Feb 18 – Feb 20
Machine learning tools for personalised diagnosis in dementia, PI: A/Prof Christopher Chen SGD$121,720
Apr 18 – Mar 19
NUHSCG/2017/Bridging/01 (NMRC/CG/M009/2017) - MACC Biomarker Discovery Bridging Fund, PI: A/Prof Christopher Chen SGD$100,000
Jul 18 – Mar 20
Functionalageing/SINGER/FY2018 - SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER) Pilot study, PI: A/Prof Christopher Chen SGD$420,000
Jul 18 – Jul 21
NMRC/CIRG/1485/2018 - Mechanisms of decline in vascular cognitive impairment, PI: A/Prof Christopher Chen SGD$1,493,000
2019
Feb 2019- Dec 2021
NUS-USYD Strategic Partnership 2019 - Intensive targeting of blood pressure to reduce dementia and small‐vessel disease in individuals who have survived an intracerebral haemorrhage: a multi‐site double‐blind placebo controlled randomized controlled trial and cognitive validity study, SGD$9925
Oct 2019 – Mar 2021
DDOP Clinical trial - Clinical assessment of the use of reverse transcriptase inhibitors in patients with mild cognitive impairment, SGD$341,000
2021
2021-2026
Prevention of and Biomarkers for Vascular Cognitive Impairment. National Medical Research Council NMRC/OFLCG/2019 PI : A/Prof Christopher Chen SGD 10,000,000
Jan 2021 – Jan 2026
NMRC Open Fund Large Collaborative Grant Call (OF-LCG) (May 2019) - Prevention of and Biomarkers for Vascular Cognitive Impairment, SGD$10,000,000
01 Aug 2021 – 31 Oct 2025
Validating Existing and Emerging Multi-modal Biomarkers of Vascular Cognitive Impairment (MOH-000707) Singapore Translational Research Investigator Award PI : A/Prof Christopher Chen SGD 5,995,800.00
01/01/2022 – 31/12/2025
INTEgRating bRain, Eye And Cardiac Research (INTER-REACH) : How the Scarecrow found a Brain, the Lion Vision to locate Courage and the Tin Man a Heart (CG21APR2010). PI : A/Prof Christopher Chen SGD 4,000,000.00